(2-METHYL-5-NITROPHENYL)BORONIC ACID

(2-METHYL-5-NITROPHENYL)BORONIC ACID - Names and Identifiers

Name	(2-Methyl-5-nitrophenyl)boronic acid
Synonyms	RARECHEM AH PB 0106 2-Methyl-5-nitrophenylboronic acid 5-Nitro-2-methylphenylboronic acid 2-METHYL-5-NITROBENZENEBORONIC ACID (2-Methyl-5-nitrophenyl)boronic acid (2-METHYL-5-NITROPHENYL)BORONIC ACID Boronic acid, B-(2-methyl-5-nitrophenyl)- 3-Borono-4-methylnitrobenzene, 2-Borono-4-nitrotoluene
CAS	100960-11-0
InChI	InChI=1/C7H8BNO4/c1-5-2-3-6(9(12)13)4-7(5)8(10)11/h2-4,10-11H,1H3

(2-METHYL-5-NITROPHENYL)BORONIC ACID - Physico-chemical Properties

Molecular Formula	C7H8BNO4
Molar Mass	180.95
Density	1.33±0.1 g/cm3(Predicted)
Melting Point	56-60°C
Boling Point	389.1±52.0 °C(Predicted)
Flash Point	189.2°C
Vapor Presure	9.41E-07mmHg at 25°C
pKa	7.00±0.58(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.563

(2-METHYL-5-NITROPHENYL)BORONIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing.
Hazard Note	Irritant

(2-METHYL-5-NITROPHENYL)BORONIC ACID - Introduction

2-methyl -5-nitrobenzene boronic acid, chemical formula CH3C6H3(NO2)COOH, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless crystalline solid.
-Melting point: about 132-135 degrees Celsius.
-Solubility: Soluble in ethanol, ether and chloroform, insoluble in water.

Use:
- 2-methyl -5-nitrobenzene boronic acid can be used as an important intermediate in organic synthesis.
-It can be nitrated to 2-methyl -5, 6-dinitrophenylboronic acid, which is an important industrial compound used to make high-energy explosives.
-It can also be used as a reagent in the field of fluorescent probes, dyes and drugs.

Preparation Method:
- 2-methyl -5-nitrobenzene boronic acid preparation method mainly has two kinds. One is obtained by the nitration of 2-methyl -1, 4-phenylenediamine, and the other is obtained by the esterification of o-nitrobenzene boric acid with 2-methyl-5-nitrobenzaldehyde.

Safety Information:
-2-Methyl-5-nitrophenylboronic acid is stable at room temperature, but avoid prolonged exposure to sunlight.
-It is a chemical and should be stored away from fire and oxidizing agents and kept sealed.
-When handling, you need to wear appropriate protective gloves and eye protection equipment to avoid direct contact.
-Seek immediate medical help in case of unforeseen conditions such as inhalation, ingestion or contact with skin.

Please note that the use and handling of chemicals should comply with the relevant local regulations and safety guidelines to ensure safe operation.

Last Update：2024-04-09 15:17:50